Persistence of Borrelia burgdorferi in Rhesus Macaques following Antibiotic Treatment of Disseminated Infection
A new study of Rhesus Monkeys clearly shows that Borrelia burgdorferi persists following long term antibiotic treatment. There are three reasons this study stands out:
- Macaques were used, not mice. It's more expensize and kinda sad, but it's a better animal host.
- Treatment was longterm and multiple antibiotics were used, ceftriaxone (4 weeks) and doxycycline (8 weeks)
- Persistence was detected using xenodiagnosis using nimphal ticks and PCR/Fluorescence
The paper was published on PLoS One so it can be accessed by everyone at: Link to Paper
